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apalutamide will lessen the extent or effect of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a strong CYP3A4 inducer, with drugs that are CYP3A4 substrates may result in decrease exposure to those remedies.Reserve concomitant prescribing of such prescriptio